Bone Perfusion Bioreactor
Grayson et al. 2010
Enables studies involving perfusion of porous, rigid scaffolds. Input format is cylindrical but can be adapted to other geometries. Main wetted materials are PDMS and polycarbonate. 6 grafts share medium and are perfused on a single channel with peristaltic pump.
Osteochondral Dual Media Perfusion Bioreactor
Chen et al. 2020
Enables co-culture of bone and cartilage, supporting each with independently controlled perfusate. Input format is cylindrical bone plugs with cartilage layer. PDMS is the main wetted material, while polycarbone forms the housing. Sterilized with autoclave. Requires 2 channels on a peristaltic pump per sample.
Multi-well Plate Perfusion and Stimulation Platform
Maidhof et al. 2011
Enables perfusion and stimulation of tissues within a 6-well plate. Main wetted materials are PDMS, polycarbonate, and carbon electrodes connected by platinum wire. Sterilized with autoclave. Requires peristaltic pump and electrical stimulator.
Medium Gradient Platform for 3D Aggregates
Cimetta et al. 2013
Enables study of a gradient of medium composition for spheroids / embryoid bodies / organoids. PDMS and polycarbonate are the main wetted materials. An additional fixture plate that does not contact the sample or fluid is made from machined aluminum. Sterilized by autoclave. Requires a syringe pump with multi-syringe capacity.