Osteochondral Dual Media Perfusion Bioreactor

Chen et al. 2020

Enables co-culture of bone and cartilage, supporting each with independently controlled perfusate. Input format is cylindrical bone plugs with cartilage layer. PDMS is the main wetted material, while polycarbone forms the housing. Sterilized with autoclave. Requires 2 channels on a peristaltic pump per sample.

Multi-tissue Co-culture with Perfused Vasculature

Chramiec et al. 2020

Enables co-culture of tissues via perfusion based shear. Main wetted materials are Polysulfone, Polypropylene, and PET film. PDMS free. Sterilize with autoclave. Requires peristaltic pump for perfusion.

Bone Perfusion Bioreactor

Greyson et al. 2010

Enables studies involving perfusion of porous, rigid scaffolds. Input format is cylindrical but can be adapted to other geometries. Main wetted materials are PDMS and polycarbonate. 6 grafts share medium and are perfused on a single channel with peristaltic pump.

Multi-well Plate Stimulation Platform

Godier-Furnémont et al. 2011

Enables stimulation of tissues within a 6-well plate. Main wetted materials are polycarbonate and carbon electrodes, connected with platinum wire. Sterilize with autoclave. Requires electrical stimulator.

Arduino-based cardiac stimulator

Ronaldson et al. 2018

Enables user-defined electrical stimulation (voltage, timing) of tissues. Interfaces with carbon electrodes connected with platinum wire.

Anatomical Osteochondral Perfusion Bioreactor

Chen et al. 2020

Enables perfusion of large, anatomic / organic shaped porous, rigid scaffolds. Main wetted materials are PDMS and polycarbonate. Sterilize with autoclave. Requires peristaltic pump for perfusion.

Medium Gradient Platform for 3D Aggregates

Cimetta et al. 2013

Enables study of a gradient of medium composition for spheroids / embryoid bodies / organoids. PDMS and polycarbonate are the main wetted materials. An additional fixture plate that does not contact the sample or fluid is made from machined aluminum. Sterilized by autoclave. Requires a syringe pump with multi-syringe capacity.

Multi-well Plate Perfusion Platform

Maidhof et al. 2010

Enables perfusion of tissues with porous soft scaffolds within a 6-well plate. Main wetted materials are PDMS and polycarbonate. Sterilized with autoclave. Requires one perfusion channel per sample on a peristaltic pump.

Multi-well Plate Perfusion and Stimulation Platform

Maidhof et al. 2011

Enables perfusion and stimulation of tissues within a 6-well plate. Main wetted materials are PDMS, polycarbonate, and carbon electrodes connected by platinum wire. Sterilized with autoclave. Requires peristaltic pump and electrical stimulator.