Our Publications

A Multi-organ Chip with Matured Tissue Niches Linked by Vascular Flow

K. Ronaldson-Bouchard et al.

2022

A Multi-organ Chip with Matured Tissue Niches Linked by Vascular Flow

Quantification of human neuromuscular function through optogenetics

O. Vila et al.

2019

Quantification of human neuromuscular function through optogenetics

Thermoplastic moulding of regenerated silk

C. Guo et al.

2020

Thermoplastic moulding of regenerated silk

milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues

M. Tamargo et al.

2021

milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues

Enzyme-Mediated Conjugation of Peptides to Silk Fibroin for Facile Hydrogel Functionalization

M. McGill et al.

2020

Enzyme-Mediated Conjugation of Peptides to Silk Fibroin for Facile Hydrogel Functionalization

In vitro models of neuromuscular junctions and their potential for novel drug discovery and development

O. Vila et al.

2019

In vitro models of neuromuscular junctions and their potential for novel drug discovery and development

Sound-guided Assessment and Localization of Pulmonary Air Leak

M. Pinezich et al.

2022

Sound-guided Assessment and Localization of Pulmonary Air Leak

Organs-on-a-chip models for biological research

G. Vunjak-Novakovic et al.

2021

Organs-on-a-chip models for biological research

Self-Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration

Y. Huang et al.

2020

Self-Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration

Human Tissue-Engineered Model of Myocardial Ischemia-Reperfusion Injury

T. Chen et al.

2019

Human Tissue-Engineered Model of Myocardial Ischemia-Reperfusion Injury

Engineered Vascularized Flaps, Composed of Polymeric Soft Tissue and Live Bone, Repair Complex Tibial Defects

I. Redenski et al.

2021

Engineered Vascularized Flaps, Composed of Polymeric Soft Tissue and Live Bone, Repair Complex Tibial Defects

Opportunities and Challenges in Cardiac Tissue Engineering From an Analysis of Two Decades of Advances

R. Zhuang et al.

2022

Opportunities and Challenges in Cardiac Tissue Engineering From an Analysis of Two Decades of Advances

Emerging Trajectories for Next Generation Tissue Engineers

D. Tavakol et al.

2021

Emerging Trajectories for Next Generation Tissue Engineers

A framework for developing sex-specific engineered heart models

R. Lock et al.

2021

A framework for developing sex-specific engineered heart models

Cell type–specific microRNA therapies for myocardial infarction

B. Liu et al.

2021

Cell type–specific microRNA therapies for myocardial infarction

Pressure-driven spreadable deferoxamine-laden hydrogels for vascularized skin flaps

L. Wu et al.

2021

Pressure-driven spreadable deferoxamine-laden hydrogels for vascularized skin flaps

In Vitro Models of Intestine Innate Immunity

T. Roh et al.

2021

In Vitro Models of Intestine Innate Immunity

Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip

K. Wagner et al.

2020

Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip

Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche

N. Dorrello et al.

2020

Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche

Heart regeneration in mouse and human: a bioengineering perspective

B. Fine et al.

2020

Heart regeneration in mouse and human: a bioengineering perspective

Cell armor for protection against environmental stress: Advances, challenges and applications in micro-...

O. Hasturk et al.

2019

Cell armor for protection against environmental stress: Advances, challenges and applications in micro-...

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

D. Chen et al.

2020

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

STK25 Inhibits PKA Signaling by Phosphorylating PRKAR1A

X. Zhang et al.

2022

STK25 Inhibits PKA Signaling by Phosphorylating PRKAR1A

Tissue-Engineered Bone Tumor as a Reproducible Human in Vitro Model for Studies of Anticancer Drugs

C. Sakolish et al.

2019

Tissue-Engineered Bone Tumor as a Reproducible Human in Vitro Model for Studies of Anticancer Drugs

Bioengineered optogenetic model of human neuromuscular junction

O. Vila et al.

2021

Bioengineered optogenetic model of human neuromuscular junction

From Silk Spinning to 3D Printing: Polymer Manufacturing using Directed Hierarchical Molecular Assembly

X. Mu et al.

2020

From Silk Spinning to 3D Printing: Polymer Manufacturing using Directed Hierarchical Molecular Assembly

Sustained Delivery of SB-431542, a Type I Transforming Growth Factor b-1 Receptor Inhibitor, to Prevent Arthrofibrosis

A. Lee et al.

2021

Sustained Delivery of SB-431542, a Type I Transforming Growth Factor b-1 Receptor Inhibitor, to Prevent Arthrofibrosis

Imaging-guided Bioreactor for De-epithelialization and Long-term cultivation of ex vivo

S. Mir et al.

2022

Imaging-guided Bioreactor for De-epithelialization and Long-term cultivation of ex vivo

Learning and synaptic plasticity in 3D bioengineered neural tissues

N. Rouleau et al.

2021

Learning and synaptic plasticity in 3D bioengineered neural tissues

Fabricating mechanically improved silk-based vascular grafts by solution control of the gel-spinning process

M. Rodriguez et al.

2019

Fabricating mechanically improved silk-based vascular grafts by solution control of the gel-spinning process

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue Rat Trachea

S. Mir et al.

2022

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue Rat Trachea

From Arteries to Capillaries: Approaches to Engineering Human Vasculature

S. Fleischer et al.

2020

From Arteries to Capillaries: Approaches to Engineering Human Vasculature

Engineering Complexity in Human Tissue Models of Cancer

K. Ronaldson-Bouchard et al.

2022

Engineering Complexity in Human Tissue Models of Cancer

Bioengineering Human Cartilage–Bone Tissues for Modeling of Osteoarthritis

J. Wu et al.

2021

Bioengineering Human Cartilage–Bone Tissues for Modeling of Osteoarthritis

Machine Learning Techniques to Classify Healthy and Diseased Cardiomyocytes by Contractility Profile

D. Teles et al.

2021

Machine Learning Techniques to Classify Healthy and Diseased Cardiomyocytes by Contractility Profile

Gut bioengineering strategies for regenerative medicine

J. O'Neill et al.

2021

Gut bioengineering strategies for regenerative medicine

Toward Studying Cognition in a Dish

N. Rouleau et al.

2021

Toward Studying Cognition in a Dish

Dynamically tunable light responsive silk-elastin-like proteins

O. Narayan et al.

2021

Dynamically tunable light responsive silk-elastin-like proteins

Synthesis and Characterization of Silk Ionomers for Layer-by-Layer Electrostatic Deposition on Individual Mammalian Cells

O. Hasturk et al.

2020

Synthesis and Characterization of Silk Ionomers for Layer-by-Layer Electrostatic Deposition on Individual Mammalian Cells

Bioengineered elastin- and silk-biomaterials for drug and gene delivery

L. Chambre et al.

2020

Bioengineered elastin- and silk-biomaterials for drug and gene delivery

Characterization of silk-hyaluronic acid composite hydrogels towards vitreous humor substitutes

N. Raia et al.

2020

Characterization of silk-hyaluronic acid composite hydrogels towards vitreous humor substitutes

Silk Hydrogels Crosslinked by the Fenton Reaction

J. Choi et al.

2019

Silk Hydrogels Crosslinked by the Fenton Reaction

Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs

A. Hozain et al.

2020

Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs

3D Printing of Silk Protein Structures by Aqueous Solvent-Directed Molecular Assembly

X. Mu et al.

2020

3D Printing of Silk Protein Structures by Aqueous Solvent-Directed Molecular Assembly

A Clinically-relevant Model of Acute Respiratory Distress
Syndrome in Human-size Swine

S. Kaslow et al.

2022

A Clinically-relevant Model of Acute Respiratory Distress
Syndrome in Human-size Swine

Matrix Deformation with Ectopic Cells Induced by Rotational Motion in Bioengineered Neural Tissues

N. Rouleau et al.

2020

Matrix Deformation with Ectopic Cells Induced by Rotational Motion in Bioengineered Neural Tissues

Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

A. Hozain et al.

2019

Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles...

A. Villasante et al.

2021

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles...

Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading

Y. Zhao et al.

2022

Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading

Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety

A. Chramiec et al.

2020

Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety

3D bioengineered tissue model of the large intestine to study inflammatory bowel disease

T. Roh et al.

2019

3D bioengineered tissue model of the large intestine to study inflammatory bowel disease

Engineering and Characterization of an Optogenetic Model of the Human Neuromuscular Junction

M. Liberman et al.

2022

Engineering and Characterization of an Optogenetic Model of the Human Neuromuscular Junction

A Guide to the Organ-on-a-Chip

C. Leung et al.

2022

A Guide to the Organ-on-a-Chip

A Framework for Developing Sex-specific Engineered Heart Models

R. Lock et al.

2021

A Framework for Developing Sex-specific Engineered Heart Models

RNA and Protein Delivery by Cell-Secreted and Bioengineered Extracellular Vesicles

B. Wang et al.

2021

RNA and Protein Delivery by Cell-Secreted and Bioengineered Extracellular Vesicles

Engineered models of tumor metastasis with immune cell contributions

P. Graney et al.

2021

Engineered models of tumor metastasis with immune cell contributions

Rheological characterization, compression, and injection molding of hydroxyapatite-silk fibroin composites

S. McNamara et al.

2021

Rheological characterization, compression, and injection molding of hydroxyapatite-silk fibroin composites

Recent advances in 3D printing with protein-based inks

X. Mu et al.

2021

Recent advances in 3D printing with protein-based inks

Harnessing organs-on-a-chip to model tissue regeneration

N. Tavakol et al.

2020

Harnessing organs-on-a-chip to model tissue regeneration

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future

M. Basil et al.

2020

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future

In Situ 3D Printing: Opportunities with Silk Inks

F. Agostinacchio et al.

2020

In Situ 3D Printing: Opportunities with Silk Inks

Assembly and Application of a Three-Dimensional Human Corneal Tissue Model

T. McKay et al.

2019

Assembly and Application of a Three-Dimensional Human Corneal Tissue Model

Tissue engineering of the heart: An evolving paradigm

Vunjak-Novakovic

2017

Tissue engineering of the heart: An evolving paradigm