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Our Publications

A Multi-organ Chip with Matured Tissue Niches Linked by Vascular Flow

K. Ronaldson-Bouchard et al.

2022

A Multi-organ Chip with Matured Tissue Niches Linked by Vascular Flow

Quantification of human neuromuscular function through optogenetics

O. Vila et al.

2019

Quantification of human neuromuscular function through optogenetics

Thermoplastic moulding of regenerated silk

C. Guo et al.

2020

Thermoplastic moulding of regenerated silk

milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues

M. Tamargo et al.

2021

milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues

From Silk Spinning to 3D Printing: Polymer Manufacturing using Directed Hierarchical Molecular Assembly

X. Mu et al.

2020

From Silk Spinning to 3D Printing: Polymer Manufacturing using Directed Hierarchical Molecular Assembly

Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

A. Hozain et al.

2019

Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

Imaging-guided Bioreactor for De-epithelialization and Long-term cultivation of ex vivo

S. Mir et al.

2022

Imaging-guided Bioreactor for De-epithelialization and Long-term cultivation of ex vivo

Organs-on-a-chip models for biological research

G. Vunjak-Novakovic et al.

2021

Organs-on-a-chip models for biological research

Self-Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration

Y. Huang et al.

2020

Self-Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration

Fabricating mechanically improved silk-based vascular grafts by solution control of the gel-spinning process

M. Rodriguez et al.

2019

Fabricating mechanically improved silk-based vascular grafts by solution control of the gel-spinning process

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue Rat Trachea

S. Mir et al.

2022

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue Rat Trachea

Emerging imaging modalities for functional assessment of donor lungs ex vivo

M. Hudock et al.

2022

Emerging imaging modalities for functional assessment of donor lungs ex vivo

From Arteries to Capillaries: Approaches to Engineering Human Vasculature

S. Fleischer et al.

2020

From Arteries to Capillaries: Approaches to Engineering Human Vasculature

Opportunities and Challenges in Cardiac Tissue Engineering From an Analysis of Two Decades of Advances

R. Zhuang et al.

2022

Opportunities and Challenges in Cardiac Tissue Engineering From an Analysis of Two Decades of Advances

A framework for developing sex-specific engineered heart models

R. Lock et al.

2021

A framework for developing sex-specific engineered heart models

In Vitro Models of Intestine Innate Immunity

T. Roh et al.

2021

In Vitro Models of Intestine Innate Immunity

Pressure-driven spreadable deferoxamine-laden hydrogels for vascularized skin flaps

L. Wu et al.

2021

Pressure-driven spreadable deferoxamine-laden hydrogels for vascularized skin flaps

Bioengineering Human Cartilage–Bone Tissues for Modeling of Osteoarthritis

J. Wu et al.

2021

Bioengineering Human Cartilage–Bone Tissues for Modeling of Osteoarthritis

Dynamically tunable light responsive silk-elastin-like proteins

O. Narayan et al.

2021

Dynamically tunable light responsive silk-elastin-like proteins

Heart regeneration in mouse and human: a bioengineering perspective

B. Fine et al.

2020

Heart regeneration in mouse and human: a bioengineering perspective

Harnessing organs-on-a-chip to model tissue regeneration

N. Tavakol et al.

2020

Harnessing organs-on-a-chip to model tissue regeneration

In Situ 3D Printing: Opportunities with Silk Inks

F. Agostinacchio et al.

2020

In Situ 3D Printing: Opportunities with Silk Inks

Assembly and Application of a Three-Dimensional Human Corneal Tissue Model

T. McKay et al.

2019

Assembly and Application of a Three-Dimensional Human Corneal Tissue Model

Tissue engineering of the heart: An evolving paradigm

G. Vunjak-Novakovic

2017

Tissue engineering of the heart: An evolving paradigm

Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs

A. Hozain et al.

2020

Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs

STK25 Inhibits PKA Signaling by Phosphorylating PRKAR1A

X. Zhang et al.

2022

STK25 Inhibits PKA Signaling by Phosphorylating PRKAR1A

Tissue-Engineered Bone Tumor as a Reproducible Human in Vitro Model for Studies of Anticancer Drugs

C. Sakolish et al.

2019

Tissue-Engineered Bone Tumor as a Reproducible Human in Vitro Model for Studies of Anticancer Drugs

Bioengineered optogenetic model of human neuromuscular junction

O. Vila et al.

2021

Bioengineered optogenetic model of human neuromuscular junction

Enzyme-Mediated Conjugation of Peptides to Silk Fibroin for Facile Hydrogel Functionalization

M. McGill et al.

2020

Enzyme-Mediated Conjugation of Peptides to Silk Fibroin for Facile Hydrogel Functionalization

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles...

A. Villasante et al.

2021

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles...

Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading

Y. Zhao et al.

2022

Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading

Learning and synaptic plasticity in 3D bioengineered neural tissues

N. Rouleau et al.

2021

Learning and synaptic plasticity in 3D bioengineered neural tissues

3D bioengineered tissue model of the large intestine to study inflammatory bowel disease

T. Roh et al.

2019

3D bioengineered tissue model of the large intestine to study inflammatory bowel disease

Technique for xenogeneic cross-circulation to support human donor lungs ex vivo

W. Wu et al.

2022

Technique for xenogeneic cross-circulation to support human donor lungs ex vivo

Opto-electromechanical quantification of
epithelial barrier function in injured and
healthy airway tissues

J. Chen et al.

2022

Opto-electromechanical quantification of
epithelial barrier function in injured and
healthy airway tissues

Engineering and Characterization of an Optogenetic
Model of the Human Neuromuscular Junction

M. Liberman et al.

2022

Engineering and Characterization of an Optogenetic
Model of the Human Neuromuscular Junction

A Guide to the Organ-on-a-Chip

C. Leung et al.

2022

A Guide to the Organ-on-a-Chip

Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts

J. Bernhard et al.

2022

Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts

Toward Studying Cognition in a Dish

N. Rouleau et al.

2021

Toward Studying Cognition in a Dish

Rheological characterization, compression, and injection molding of hydroxyapatite-silk fibroin composites

S. McNamara et al.

2021

Rheological characterization, compression, and injection molding of hydroxyapatite-silk fibroin composites

Engineered models of tumor metastasis with immune cell contributions

P. Graney et al.

2021

Engineered models of tumor metastasis with immune cell contributions

Gut bioengineering strategies for regenerative medicine

J. O'Neill et al.

2021

Gut bioengineering strategies for regenerative medicine

Recent advances in 3D printing with protein-based inks

X. Mu et al.

2021

Recent advances in 3D printing with protein-based inks

Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche

N. Dorrello et al.

2020

Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche

Synthesis and Characterization of Silk Ionomers for Layer-by-Layer Electrostatic Deposition on Individual Mammalian Cells

O. Hasturk et al.

2020

Synthesis and Characterization of Silk Ionomers for Layer-by-Layer Electrostatic Deposition on Individual Mammalian Cells

Characterization of silk-hyaluronic acid composite hydrogels towards vitreous humor substitutes

N. Raia et al.

2020

Characterization of silk-hyaluronic acid composite hydrogels towards vitreous humor substitutes

Cell armor for protection against environmental stress: Advances, challenges and applications in micro-...

O. Hasturk et al.

2019

Cell armor for protection against environmental stress: Advances, challenges and applications in micro-...

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

D. Chen et al.

2020

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

3D Printing of Silk Protein Structures by Aqueous Solvent-Directed Molecular Assembly

X. Mu et al.

2020

3D Printing of Silk Protein Structures by Aqueous Solvent-Directed Molecular Assembly

A Clinically-relevant Model of Acute Respiratory Distress
Syndrome in Human-size Swine

S. Kaslow et al.

2022

A Clinically-relevant Model of Acute Respiratory Distress
Syndrome in Human-size Swine

Matrix Deformation with Ectopic Cells Induced by Rotational Motion in Bioengineered Neural Tissues

N. Rouleau et al.

2020

Matrix Deformation with Ectopic Cells Induced by Rotational Motion in Bioengineered Neural Tissues

In vitro models of neuromuscular junctions and their potential for novel drug discovery and development

O. Vila et al.

2019

In vitro models of neuromuscular junctions and their potential for novel drug discovery and development

Sustained Delivery of SB-431542, a Type I Transforming Growth Factor b-1 Receptor Inhibitor, to Prevent Arthrofibrosis

A. Lee et al.

2021

Sustained Delivery of SB-431542, a Type I Transforming Growth Factor b-1 Receptor Inhibitor, to Prevent Arthrofibrosis

Sound-guided Assessment and Localization of Pulmonary Air Leak

M. Pinezich et al.

2022

Sound-guided Assessment and Localization of Pulmonary Air Leak

Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety

A. Chramiec et al.

2020

Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety

Human Tissue-Engineered Model of Myocardial Ischemia-Reperfusion Injury

T. Chen et al.

2019

Human Tissue-Engineered Model of Myocardial Ischemia-Reperfusion Injury

Engineering and Characterization of an Optogenetic Model of the Human Neuromuscular Junction

M. Liberman et al.

2022

Engineering and Characterization of an Optogenetic Model of the Human Neuromuscular Junction

Engineered Vascularized Flaps, Composed of Polymeric Soft Tissue and Live Bone, Repair Complex Tibial Defects

I. Redenski et al.

2021

Engineered Vascularized Flaps, Composed of Polymeric Soft Tissue and Live Bone, Repair Complex Tibial Defects

Challenges and opportunities for the next generation of cardiovascular tissue engineering

S. Cho et al.

2022

Challenges and opportunities for the next generation of cardiovascular tissue engineering

Progress in multicellular human cardiac organoids for clinical applications

H Kim et al.

2022

Progress in multicellular human cardiac organoids for clinical applications

Engineering Complexity in Human Tissue Models of Cancer

K. Ronaldson-Bouchard et al.

2022

Engineering Complexity in Human Tissue Models of Cancer

Emerging Trajectories for Next Generation Tissue Engineers

D. Tavakol et al.

2021

Emerging Trajectories for Next Generation Tissue Engineers

A Framework for Developing Sex-specific Engineered Heart Models

R. Lock et al.

2021

A Framework for Developing Sex-specific Engineered Heart Models

Cell type–specific microRNA therapies for myocardial infarction

B. Liu et al.

2021

Cell type–specific microRNA therapies for myocardial infarction

RNA and Protein Delivery by Cell-Secreted and Bioengineered Extracellular Vesicles

B. Wang et al.

2021

RNA and Protein Delivery by Cell-Secreted and Bioengineered Extracellular Vesicles

Machine Learning Techniques to Classify Healthy and Diseased Cardiomyocytes by Contractility Profile

D. Teles et al.

2021

Machine Learning Techniques to Classify Healthy and Diseased Cardiomyocytes by Contractility Profile

Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip

K. Wagner et al.

2020

Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip

Bioengineered elastin- and silk-biomaterials for drug and gene delivery

L. Chambre et al.

2020

Bioengineered elastin- and silk-biomaterials for drug and gene delivery

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future

M. Basil et al.

2020

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future

Silk Hydrogels Crosslinked by the Fenton Reaction

J. Choi et al.

2019

Silk Hydrogels Crosslinked by the Fenton Reaction

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